East 6.4 Base: MAMS

This annual license fee is for a single designated desktop digital download license.

Requirements - Purchase of East BASE, MULTIARM, and SEQUENTIAL Modules

Multi-Arm Multi-Stage (MAMS) is an East module that offers the ability to design and monitor multi-arm multi-stage studies with options for early stopping, dose selection, and sample size re-estimation. It has two features: 

• The group sequential theory extended for multi-arm setup (Gao et al., 2014) has been implemented for normal endpoint.
• The multi-arm two-stage design using p-value combination approach (Posch et al., 2005) has been implemented for both normal and binomial endpoints.